HPIC Separation of Tautomsric Compounds of 4-Aminoisoxazolyl-1,2-Naphthoquinones

Abstract
A sensitive and efficient method for determining a mixture of 4-aminoisoxazolyl-1,2-naphthoquinones isomers was developed using high performance liquid chromatography. The assay also is stability indicating, because precursors and isomerization products can be determined simultaneously. The results obtained are in agreement with those obtained by UV spectroscopy.

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