Tetanus Toxoid Loaded Nanoparticles from Sulfobutylated Poly(Vinyl Alcohol)-Graft-Poly(Lactide-co-Glycolide): Evaluation of Antibody Response After Oral and Nasal Application in Mice
- 1 January 2001
- journal article
- research article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 18 (3) , 352-360
- https://doi.org/10.1023/a:1011063232257
Abstract
Purpose. Aim of the study was the evaluation of the potential of novel tetanus toxoid (TT) loaded nanoparticles (NP) for electing an immune response in mice against TT. Methods. Six week-old female...Keywords
This publication has 22 references indexed in Scilit:
- Systemic and mucosal immune responses of mice to aluminium-adsorbed or aluminium-non-adsorbed tetanus toxoid administered intranasally with recombinant cholera toxin B subunitVaccine, 1998
- Large molecule and particulate uptake in the nasal cavity: the effect of size on nasal absorptionAdvanced Drug Delivery Reviews, 1998
- INTERACTION OF ANTIGENS AND ANTIBODIES AT MUCOSAL SURFACESAnnual Review of Microbiology, 1997
- Salivary, gut, vaginal and nasal antibody responses after oral immunization with biodegradable microparticlesVaccine, 1997
- Report of the Expert Panel VI Concerted efforts in the field of mucosal immunologyVaccine, 1996
- ANTIGEN SAMPLING ACROSS EPITHELIAL BARRIERS AND INDUCTION OF MUCOSAL IMMUNE RESPONSESAnnual Review of Immunology, 1996
- New strategies for using mucosal vaccination to achieve more effective immunizationVaccine, 1994
- Immune Response to Nasal Delivery of Antigenically Intact Tetanus Toxoid Associated with Poly(l-lactic acid) Microspheres in Rats, Rabbits and Guinea-pigsJournal of Pharmacy and Pharmacology, 1993
- Nanoparticle Uptake by the Rat Gastrointestinal Mucosa: Quantitation and Particle Size DependencyJournal of Pharmacy and Pharmacology, 1990
- Dependence on particle size in the phagocytosis of Latex particles by rabbit alveolar macrophages cultured in vitro.The Journal of Toxicological Sciences, 1983