Nigrosporolide, a Plant Growth-Inhibiting Macrolide from the MouldNigrospora sphaerica

Abstract
Bioassay-directed fractionation of an extract from the fungus Nigrospora sphaerica (strain UK181RRC) yielded a new 14-membered lactone, named nigrosporolide, whose structure was established by spectroscopic techniques. This compound inhibited the growth of etiolated wheat coleoptiles.

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