A hydrogen-bonding triad stabilizes the chemical transition state of a group I ribozyme
Open Access
- 31 March 1999
- journal article
- Published by Elsevier in Chemistry & Biology
- Vol. 6 (3) , 153-165
- https://doi.org/10.1016/s1074-5521(99)89007-3
Abstract
No abstract availableKeywords
This publication has 49 references indexed in Scilit:
- Direct Demonstration of the Catalytic Role of Binding Interactions in an Enzymatic ReactionBiochemistry, 1998
- Effects of Mg2+ and the 2‘ OH of Guanosine on Steps Required for Substrate Binding and Reactivity with the Tetrahymena Ribozyme Reveal Several Local Folding TransitionsBiochemistry, 1997
- MECHANISTIC ASPECTS OF ENZYMATIC CATALYSIS: Lessons from Comparison of RNA and Protein EnzymesAnnual Review of Biochemistry, 1997
- Dissection of the Role of the Conserved G.cntdot.U Pair in Group I RNA Self-SplicingBiochemistry, 1994
- Tertiary interactions with the internal guide sequence mediate docking of the P1 helix into the catalytic core of the Tetrahymena ribozymeBiochemistry, 1993
- Binding of guanosine and 3' splice site analogs to a Group I ribozyme: Interactions with functional groups of guanosine and with additional nucleotidesBiochemistry, 1993
- Crystallographic studies of the catalytic mechanism of the neutral form of fructose-1,6-bisphosphataseBiochemistry, 1993
- Site-Specific Modification of Pre-mRNA: the 2′-Hydroxyl Groups at the Splice SitesScience, 1992
- Comparison of binding of mixed ribose-deoxyribose analogs of CUCU to a ribozyme and to GGAGAA by equilibrium dialysis: evidence for ribozyme specific interactions with 2'-hydroxy groupsBiochemistry, 1991
- Group I Intron Self-Splicing with Adenosine: Evidence for a Single Nucleoside-Binding SiteScience, 1991