Structure‐Activity Relationship Studies of CNS Agents, Part 26 4‐[2‐(Cycloalkanecarboxamido)ethyl]‐1‐(2‐methoxyphenyl)‐piperazines: High‐Affinity 5‐HT_1A Agonists

This publication has 15 references indexed in Scilit:

• New (2-Methoxyphenyl)piperazine Derivatives as 5-HT1A Receptor Ligands with Reduced .alpha.1-Adrenergic Activity. Synthesis and Structure-Affinity Relationships
  Journal of Medicinal Chemistry, 1995
• Structure-Activity Relationship Studies of CNS Agents, XXI: Two Derivatives of 1-(o-Methoxyphenyl)piperazine with an Opposite Function at 5-HT1A Receptors
  Archiv der Pharmazie, 1995
• Structure-affinity relationship studies on 5-HT1A receptor ligands. 1. Heterobicyclic phenylpiperazines with N4-alkyl substituents
  Journal of Medicinal Chemistry, 1993
• Structure-activity relationship studies of central nervous system (CNS) agents. 5. Effect of the hydrocarbon chain on the affinity of 4-substituted 1-(3-chlorophenyl)piperazines for 5-HT1A receptor sites
  Journal of Medicinal Chemistry, 1992
• The putative 5-HT1A receptor antagonists NAN-190 and BMY 7378 are partial agonists in the rat dorsal raphe nucleus in vitro
  European Journal of Pharmacology, 1992
• Concepts for the design of 5‐HT_1A serotonin agonists and antagonists
  Drug Development Research, 1992
• Analogs of the 5-HT1A serotonin antagonist 1-(2-methoxyphenyl)-4-[4-(2-phthalimido)butyl]piperazine with reduced .alpha.1-adrenergic affinity
  Journal of Medicinal Chemistry, 1991
• The behavioural, but not the hypothermic or corticosterone, response to 8-hydroxy-2-(di-n-propylamino)-tetralin, is antagonized by nan-190 in the rat
  Neuropharmacology, 1990
• N-(phthalimidoalkyl) derivatives of serotonergic agents: a common interaction at 5-HT1A serotonin binding sites?
  Journal of Medicinal Chemistry, 1989
• Arylpiperazine derivatives as high-affinity 5-HT1A serotonin ligands
  Journal of Medicinal Chemistry, 1988