Remineralization of Artificial Caries Lesions by Stannous Fluoride

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Abstract
The remineralizing property of SnF2 was studied by treating artificial white spot enamel lesions for 0.5, 6 and 24 h and 1 week in a 4% SnF2 solution at 50 °C. Remineralization as opposed to recalcification was observed in all treated samples and was studied using microradiography and microprobe analysis. It appeared that remineralization started in the outer part of the intact surface layer covering the sub-surface lesion. With increasing time, the centre of the sub-surface lesion became remineralized. In a fully remineralized lesion it was no longer possible to distinguish between the surface layer and the sub-surface lesion. Some sections appeared to be fully remineralized after only 6 h treatment with SnF2. Microprobe analysis showed that the variation in density was highly correlated with the Sn concentration. Some possible mechanisms and reactions that may be involved in this remineralization are discussed.

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