A place for thioether chemistry in cellular copper ion recognition and trafficking
- 1 March 2008
- journal article
- research article
- Published by Springer Nature in Nature Chemical Biology
- Vol. 4 (3) , 148-151
- https://doi.org/10.1038/nchembio0308-148
Abstract
Over the last decade, cysteine thiolate ligands have been shown to be critical to the Cu(I) (cuprous) binding chemistry of many cytosolic metallochaperone and metalloregulatory proteins involved in copper physiology. More recently, the thioether group of methionine has begun to emerge as an important Cu(I) ligand for trafficking proteins in more oxidizing cellular environments.Keywords
This publication has 31 references indexed in Scilit:
- Cu(I) recognition via cation-π and methionine interactions in CusFNature Chemical Biology, 2007
- Synthesis and X‐ray Characterization of Mono‐ and Polynuclear Thiolatocopper(I) Complexes: The Effect of Steric Bulk on Coordination Number and NuclearityEuropean Journal of Inorganic Chemistry, 2007
- Copper trafficking to the mitochondrion and assembly of copper metalloenzymesBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2006
- A Mets Motif Peptide Found in Copper Transport Proteins Selectively Binds Cu(I) with Methionine-Only CoordinationInorganic Chemistry, 2005
- X-Ray Absorption and NMR Spectroscopic Studies of CopZ, a Copper Chaperone in Bacillus subtilis: The Coordination Properties of the Copper IonBiochemistry, 2003
- The PcoC Copper Resistance Protein Coordinates Cu(I) via Novel S-Methionine InteractionsJournal of the American Chemical Society, 2002
- Undetectable Intracellular Free Copper: The Requirement of a Copper Chaperone for Superoxide DismutaseScience, 1999
- The Menkes Disease Protein Binds Copper via Novel 2-Coordinate Cu(I)−Cysteinates in the N-Terminal DomainJournal of the American Chemical Society, 1998
- Preparation, Spectroscopic Characterization, and Molecular Structure of Copper(I) Aliphatic Thiolate ComplexesInorganic Chemistry, 1998
- Preparation, crystal structure, and spectroscopic characterization of [NEt4]2[Cu(SPh)3]Inorganic Chemistry, 1984