Plaque Assay for the Mason-Pfizer Monkey Virus2

Abstract
Human cells infected with the Mason-Pfizer monkey virus (MP-MV) form syncytia when overlaid with human glioma cells transformed by Rous sarcoma virus (KC cells). This observation allowed the development of a plaque assay, the results of which correlated directly with those from measurements of viral reverse transcriptase in culture fluids and immunologic assays or one of the virion structural proteins.

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