High doses of fluphenazine enanthate in schizophrenia: A CONTROLLED STUDY

Abstract
Treatment with fluphenazine enanthate in higher doses than normal (10-20 times higher) may give reduction in psychopathology beyond what can be obtained with normal doses. In 4 patients the symptom reduction on high doses was pronounced. The high fluphenazine plasma levels demonstrated did not increase extrapyramidal and general side effects. Certain non-responding patients may need a higher plasma level of a neuroleptic drug than the average patient.

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