ASP85TYR POLYMORPHISM IN THE UDP-GLUCURONOSYLTRANSFERASE (UGT) 2B15 GENE AND THE RISK OF PROSTATE CANCER
- 1 June 2004
- journal article
- Published by Wolters Kluwer Health in Journal of Urology
- Vol. 171 (6 Part 1) , 2484-2488
- https://doi.org/10.1097/01.ju.0000117748.44313.43
Abstract
Purpose: An amino acid changing polymorphism in the UDP-glucuronosyltransferase (UGT) 2B15 gene has been described at codon 85 (aspartate>tyrosine). The UGT2B1585Asp allele exhibits 2-fold ...Keywords
This publication has 11 references indexed in Scilit:
- Relative Enzymatic Activity, Protein Stability, and Tissue Distribution of Human Steroid-Metabolizing UGT2B Subfamily MembersEndocrinology, 2001
- An Allele-Specific Polymerase Chain Reaction Method for the Determination of the D85Y Polymorphism in the Human UDPGlucuronosyltransferase 2B15 Gene in a Case-Control Study of Prostate CancerAnnals of Surgical Oncology, 2000
- Prostate cancer risk and polymorphism in 17 hydroxylase (CYP17) and steroid reductase (SRD5A2)Carcinogenesis: Integrative Cancer Research, 1999
- The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergencePharmacogenetics, 1997
- Isolation and characterization of UGT2B15(Y85): a UDP glucuronosyltransferase encoded by a polymorphic genePharmacogenetics, 1997
- Prospective Study of Sex Hormone Levels and Risk of Prostate CancerJNCI Journal of the National Cancer Institute, 1996
- Prostate Cancer in Relation to Diet, Physical Activity, and Body Size in Blacks, Whites, and Asians in the United States and CanadaJNCI Journal of the National Cancer Institute, 1995
- Characterization of a cloned human dihydrotestosterone/androstanediol UDP-glucuronosyltransferase and its comparison to other steroid isoformsBiochemistry, 1993
- UDP-glucuronosyltransferases: a family of detoxifying enzymesTrends in Pharmacological Sciences, 1990
- DNA sequencing with chain-terminating inhibitorsProceedings of the National Academy of Sciences, 1977