Colorectal Liver Metastases

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Abstract
Colorectal cancer is the fourth most common type of cancer in the Western world and is the second leading cause of cancer-related deaths in the United States.1 Approximately 35% to 55% of patients with colorectal cancer develop hepatic metastases during the course of their disease.2 Surgical resection of colorectal liver metastases is associated with long-term survival rates of 35% to 58%.3-9 Radiofrequency ablation (RFA) has been proposed as a means to increase the number of patients eligible for liver-directed therapy. In patients with extensive metastatic disease who would otherwise be ineligible for resection, ablative approaches are often used instead of or combined with hepatic resection.3,10-12