To determine the health-related quality of life in patients with Crohn disease and ulcerative colitis, as well as to evaluate differences according to sex, type of disease and other sociodemographic variables. Cross sectional study of 100 outpatients in the Digestive Service of the Navarre Hospital Complex.A questionnaire with sociodemographic and clinical variables was used, as well as a version of the Inflammatory Bowel Disease Questionnaire-32 adapted to Spanish, in order to measure quality of life. The average score of the questionnaire on quality of life was 166 points (D.T.=40.06) out of a maximum of 232. Statistically significant differences were found according to type of disease (p=0.005)and sex (p=0.001). People with Crohn disease or females perceive a worse quality of life related to health in comparison to patients with ulcerative colitis or men.