Inhibitory Effect of Pyrophosphate, Citrate, Magnesium and Chondroitin Sulphate in Calcium Oxalate Urolithiasis
- 1 September 1989
- journal article
- research article
- Published by Wiley in British Journal of Urology
- Vol. 64 (3) , 235-237
- https://doi.org/10.1111/j.1464-410x.1989.tb06004.x
Abstract
Summary— The inhibitory capacity of pyrophosphate, citrate, magnesium and chondroitin sulphate was investigated, using the urine of 21 calcium oxalate stone‐forming patients without metabolic alterations. The inhibitory effect of these substances was assessed by a combination of nephelometry (light scattering) and optical microscopy. The results showed that citrate and magnesium had an inhibitory effect in a significant number of cases. Pyrophosphate and chondroitin sulphate had a less marked effect. The main urinary lithogenic biochemical parameters of the patients were also studied to see if there was a relationship between them and the inhibitory capacity of the compounds.This publication has 5 references indexed in Scilit:
- Calcium Oxalate Precipitation in a Flow System: An Attempt to Simulate The Early Stages of Stone Formation in the Renal TubulesJournal of Urology, 1986
- Pathogenesis of UrolithiasisPublished by Springer Nature ,1985
- Inhibitors of the growth and aggregation of calcium oxalate crystals in vitroClinica Chimica Acta; International Journal of Clinical Chemistry, 1973