Mannanase Man26A fromCellulomonas fimihas a mannan-binding module

Abstract
A modular mannanase (Man26A) from the bacterium Cellulomonas fimi contains a mannan-binding module (Man26Abm) that binds to soluble but not to insoluble mannans. Man26Abm does not bind to cellulose, chitin or xylan. The Kd for binding of Man26Abm to locust bean gum (LBG) is ∼0.2 μM. Man26A is the first mannanase reported to contain a mannan-binding module.