Drugs and the fetus

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Abstract
Drugs can cause fetal death or damage at any stage of pregnancy. Anticancer drugs, for example, inhibit cell replication and so may cause the death of the embryo during blastocyst formation (0-16 days). Later in pregnancy (second and third trimester), drugs such as β blockers may cause general retardation of growth, while others may affect maturation of specific organ systems—for example, angiotensin converting enzyme inhibitors cause abnormalities of renal function and skull development.2 …