Mta, a maternally inherited cell surface antigen of the mouse, is transmitted in the egg.
- 1 September 1982
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 79 (17) , 5362-5366
- https://doi.org/10.1073/pnas.79.17.5362
Abstract
Mta is a maternally transmitted cell surface antigen found in most mouse strains. It serves as a target for unrestricted T killer cells. All 49 embryos transferred between positive and negative mothers, even as early as 10-15 h after fertilization, developed into mice with the Mta type of their original mothers. Therefore the genetic element that determines expression of Mta must be transmitted by the egg. Mta+ and Mta- lymphocytes, coexisting for months in lethally irradiated F1 mice reconstituted with a mixture of parental bone marrow cells, retained their Mta type. Mta does not spread by infection.This publication has 8 references indexed in Scilit:
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