Myo-inositol-1-phosphate synthase from streptomyces griseus (Studies on the biosynthesis of cyclitols, XXXVIII1)
- 1 May 1979
- journal article
- research article
- Published by Springer Nature in Molecular and Cellular Biochemistry
- Vol. 25 (1) , 43-46
- https://doi.org/10.1007/bf00211140
Abstract
It could be shown that Streptomyces griseus, the microorganism producing the antibiotic streptomycin and also mutant strains of this species that cannot synthesize streptomycin, possess myo-inositol-1-phosphate synthase (EC 5.5.1.4), the enzyme cyclizing D-glucose 6-phosphate. The enzyme isolated from that organism is extremely instable, its molecular weight is approximately 260,000, and it requires a divalent metal ion for its activity. This is the first instance that an enzyme of this specificity has been found in a prokaryotic organism.This publication has 9 references indexed in Scilit:
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