Variations in behavioral inhibition following different septal lesions in rats.

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Abstract
It was found that lesions which produced extensive damage to the septohippocampal system and the lateral septal nuclei produced evidence of perseverative responding in a position-habit reversal task but did not alter passive avoidance. Male albino Holtzman rats served as Ss in 2 experiments. Lesions restricted primarily to the lateral septal nuclei impaired passive avoidance but had little effect on the reversal of a position habit. Damage restricted to either the medial or lateral nuclei enhanced the acquisition of active-avoidance responses in a shuttle box. (19 ref.) (PsycINFO Database Record (c) 2006 APA, all rights reserved)

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