Homonuclear one- and two-dimensional nuclear Overhauser effect experiments and spin-echo correlated spectroscopy. Application to prostaglandin E1 and 6-keto-prostaglandin E1
- 15 October 1982
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 60 (20) , 2617-2624
- https://doi.org/10.1139/v82-376
Abstract
Nuclear Overhauser effect one-dimensional and two-dimensional nuclear magnetic resonance experiments are reported for prostaglandin E1. The two-dimensional nuclear Overhauser effect measurements are combined with spin-echo correlated spectroscopy in order to assign the complete high-field proton magnetic resonance spectrum of 6-keto-prostaglandin E1. The advantages of these two-dimensional techniques are illustrated in these studies. It is also observed that the 6-keto-prostaglandin E1 H-10α proton is substituted more readily by deuterium than are the other protons α to the keto groups.Keywords
This publication has 2 references indexed in Scilit:
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- Intramolecular proton nuclear Overhauser effect study of the solution conformation of valinomycin in dimethyl sulfoxideBiochemistry, 1976