Increased Insulin Sensitivity and Insulin Binding to Monocytes after Physical Training

Abstract
We studied the effect of physical training on in vivo tissue sensitivity to insulin and insulin binding to monocytes in six previously untrained healthy adults. Physical training (one hour of cycle-ergometer exercise four times per week for six weeks) failed to alter body weight but resulted in a 20 per cent increase (P2 max) and a 30 per cent increase (P2 max (P125I]insulin to monocytes also rose by 35 per cent after physical training (P<0.02), primarily because of an increase in the concentration of insulin receptors.