Restriction of Herpes Simplex Virus Type 1 Replication in Oncornavirus-Transformed Cells2
- 1 March 1974
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 52 (3) , 757-761
- https://doi.org/10.1093/jnci/52.3.757
Abstract
Replication of herpes simplex virus type 1 (HSV-1) was studied in various cell lines infected with and/or transformed by oncornaviruses. HSV-1 production was completely inhibited in calls transformed by sarcoma viruses of murine, feline, and avian origin. Replication of HSV-1 was only slightly restricted in cells infected with a murine leukemia virus. Associated with the HSV-1 restriction was a concomitant inhibition of viral DNA synthesisKeywords
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