Isolation and Characterization of New Anti-HIV and Cytotoxic Leads from Plants, Marine, and Microbial Organisms
- 1 May 1997
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 60 (5) , 431-438
- https://doi.org/10.1021/np970031g
Abstract
New cytotoxic isomalabaricane triterpenes have been isolated from a sponge Stelletta sp. (1−7); anti-HIV pterocarpans (8 and 9) and isoflavanoids (12−16 and 18) were elucidated from two tropical plants in the genus Erythrina; and anti-HIV enniatins (20 and 22−23) were characterized from fungi in the genera Fusarium and Alternaria. The enniatins were evaluated for in vivo anti-HIV activity in the hollow fiber assay.Keywords
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