A convenient method for the synthesis of baicalein (5,6,7-trihydroxyflavone) and 4′-methylgamatin (4-methoxy-3-methyl-7-phenylfuro-[3,2-g][1]benzopyran-5-one)
- 1 January 1973
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- p. 503-505
- https://doi.org/10.1039/p19730000503
Abstract
We report a modified synthesis of baicalein by Dakin oxidation of 6-acetyl-5,7-dihydroxyflavone (I)(obtained by condensation of phloroacetophenone with ethyl benzoylacetate), and the elaboration of a furan ring on structure (I) by a conventional method to give 4′-methylgamatin.Keywords
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