The Effect of Controlled Halothane Anaesthesia on Splanchnic Oxygen Consumption in the Dog
- 1 June 1975
- journal article
- research article
- Published by Wiley in Acta Anaesthesiologica Scandinavica
- Vol. 19 (3) , 238-244
- https://doi.org/10.1111/j.1399-6576.1975.tb05245.x
Abstract
The influence of halothane anaesthesia on splanchnic oxygen flow and oxygen uptake was studied in seven dogs. Mean oxygen supply to the liver and the portally‐drained tissues decreased significantly to 44% and 53% of control values, respectively, while mean oxygen consumption diminished insignificantly to 68% and 82% of control values, respectively. There was a fall in the oxygen flow/oxygen consumption ratio in all animals following halothane. The relatively unimpaired oxygen uptake, in spite of a diminished oxygen supply, led to an increased extraction of oxygen by the tissues. Some factors affecting oxygen utilisation during halothane anaesthesia are discussed.ZUSAMMENFASSUNG: An 7 Hunden wurde der Einfluß einer Halothannarkose auf den Sauerstoff‐Flow und die Saurrstoffaufnahme im Splanchicusbereich untersucht. Die Mittelwerte der Sauerstoffversorgung der Lebcr und der durch die Pfortader drainierten Gewebe ficl signifikant auf 44% bzw. 53% der Kontrollwertr, während der mittlere Saucrstoffverbrauch nicht‐signifikant auf 68% bzw. 82% der Kontrollwerte absank. Unter Halothan kam es bci allen Tieren zu einem Absinken der Relation Saucrstoffzufuhr/Sauerstoffverbrauch. Die relativ ungestorte Sauerstoffaufnahme bei gleichzeitig verminderter Sauerstoffzufuhr fübrte zu einer erhöhten Sauerstoffextraktion durch die Gewebe. Einige Faktoren, die Sauerstoffausnutzung während der Halothannarkose betreffend, werden diskutiert.This publication has 27 references indexed in Scilit:
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