Circulation of H + and K + Across the Plasma Membrane Is Not Obligatory for Bacterial Growth
- 22 July 1977
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 197 (4301) , 372-373
- https://doi.org/10.1126/science.69317
Abstract
Streptococcus faecalis grows normally in the presence of gramicidin and other ionophores under conditions such that there is no gradient of pH or of electrical potential across the plasma membrane and that currents of H+, K+, and Na+ are short-circuited. Growth requires a rich medium, a slightly alkaline pH, and a high concentration of external K+. The proton circulation maintains the cytoplasmic pH and pools of ions and other metabolites but is not obligatory for biosynthetic functions including DNA replication, cell division, or assembly of the structural framework of the cell.This publication has 16 references indexed in Scilit:
- ION CURRENTS AND PHYSIOLOGICAL FUNCTIONS IN MICROORGANISMSAnnual Review of Microbiology, 1977
- Membranes and Energy Transduction in Bacteria1 1Abbreviations: Δψ, membrane potential; ΔpH, pH gradient; Δp, proton-motive force. These are related by: Δp = Δψ - (23RT/F) ΔpH ≅ Δψ - 60 ΔpH. ANS, l-anilino-8-naphthalene sulfonate; DCCD, N, N'-dicyclohexylcarbodiimide; CCCP, carbonylcyanide-m-chlorophenylhydrazone; HOQNO, hydroxyquinoline-N-oxide; PEP, phosphoenolpyruvic acid. EDTA, ATP, GTP, DNA, NAD(H), and NADP(H) have their usual meanings.Published by Elsevier ,1977
- The Energetics of Bacterial Active TransportAnnual Review of Biochemistry, 1975
- Protonmotive force in fermenting Streptococcuslactis 7962 in relation to sugar accumulationBiochemical and Biophysical Research Communications, 1974
- Estimations of membrane potentials in Streptococcus faecalis by means of a fluorescent probeBiochemical and Biophysical Research Communications, 1974
- Cation Transport in Bacteria: K+, Na+, and H+Published by Elsevier ,1974
- Cation transport and electrogenesis byStreptococcus faecalisThe Journal of Membrane Biology, 1972
- Cation transport and electrogenesis byStreptococcus faecalisThe Journal of Membrane Biology, 1972
- CHEMIOSMOTIC COUPLING IN OXIDATIVE AND PHOTOSYNTHETIC PHOSPHORYLATIONBiological Reviews, 1966
- Quantitative amino acid assimilation in homofermentative metabolismArchives of Biochemistry and Biophysics, 1953