Darier's disease and retinitis pigmentosa; is there a pathogenetic relationship?

Abstract
Two brothers with Darier''s disease and concomitant retinitis pigmentosa are reported. To our knowledge, these are the first cases with this combination of symptoms described in the literature. The dermatological conditions occurring with retinitis pigmentosa are reviewed. A disturbance in retinoids or retinoid binding proteins as a possible cause of both diseases is discussed.