Basic Biological Sciences
- 1 August 1981
- journal article
- research article
- Published by SAGE Publications in Journal of Dental Research
- Vol. 60 (8) , 1427-1431
- https://doi.org/10.1177/00220345810600080601
Abstract
The circulatory uptake and urinary excretion of topical fluoride were investigated by applying a sodium fluoride solution containing 18F for six min to healthy gingiva of four adult dogs. Blood and urine samples were taken at regular intervals. Maximal fluoride in blood represented 0.02-0.05% of the applied dose and occurred four min after completion of the application. By 6.0 h, 0.02-0.06% of the applied dose had been excreted in urine. Preliminary data showed that this represented about 8.8% of the fluoride absorbed through the gingiva.This publication has 14 references indexed in Scilit:
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