Effect of Intraluminal Pressure on Enterochromaffin Cells in the Rat Duodenum.

Abstract
Summary The number of recognizable enterochromaffin cells in the mucosa of the rat duodenum is significantly reduced in response to increased intraluminal pressure. It is suggested that these findings offer histochemical corroboration for the concept that pressure is one mechanism mediating release of 5-hydroxytryptamine from intestinal mucosa.