The Colton blood group locus
- 10 September 1988
- journal article
- research article
- Published by Wiley in Transfusion
- Vol. 28 (5) , 435-438
- https://doi.org/10.1046/j.1537-2995.1988.28588337331.x
Abstract
Accumulated family information was compiled in an attempt to verify the chromosomal location of the Colton blood group locus (CO). Two‐point linkage analysis of CO and 46 other polymorphic loci excludes CO from 1p36 to 1q23, 3q21 to 3q26, 4q13 to 4q28, 6p24 to 6 cen, and 19p13.2 to 19 cen and from linkage groups bounded by ABO and ORM, PI and IGHG, and HP and GOT2. The dwindling odds of linkage between CO:JK are reinforced (z =−5.28 at theta = 0.20). Close linkage of CO with ACP1 and D2S5 could not be demonstrated. The proposed chromosome 2 location of CO is therefore questioned.This publication has 7 references indexed in Scilit:
- The Kidd (JK) blood group locus assigned to chromosome 18 by close linkage to a DNA-RFLPHuman Genetics, 1987
- Two RFLPs identified by a human chromosome #2 clone at 2p15–2p16 (HGM8 assignment no. D2S5)Nucleic Acids Research, 1985
- Report of the committee on the genetic constitution of chromosomes 1 and 2Cytogenetic and Genome Research, 1985
- Analysis of linkage relationships of Co, Jk and K with each other and with chromosome 2 loci ACP1 and KmAnnals of Human Genetics, 1982
- Colton blood groups: indication of linkage with the Kidd (Jk) system as support for assignment to chromosome 7Clinical Genetics, 1977
- Colton Blood Groups in Canadian Caucasians: Frequencies, Inheritance and Linkage Analysis1Vox Sanguinis, 1977
- Likely linkage: Inv with JkHuman Genetics, 1977