Host-Parasite Relationships of Fasciola hepatica in the White Mouse. VII. Effects of Anti-Worm Incubate Sera on Transferred Worms and Successful Vaccination with a Crude Incubate Antigen
- 1 April 1976
- journal article
- research article
- Published by JSTOR in Journal of Parasitology
- Vol. 62 (2) , 232-236
- https://doi.org/10.2307/3279274
Abstract
Mouse antisera against the 16-day-old worm incubate and sera from 25-day infections in mice debilitated migrating flukes in recipient animals was measured by worm recovery and host mortality. Mouse antisomatic and 100-day infection sera produced no such effects. Host mortality was significantly lower after challenge in mice given 1 i.p. immunizing injection of the worm incubate; worm recovery was not significantly reduced. Injections at 2, 7, 12 and 24 h with the worm incubate elaborated over a 24-h period protected 75% of the mice from infection after challenge and reduced the worm burden by 83.3%.This publication has 2 references indexed in Scilit:
- Observations on the Survival In vitro of Bacteria-Free Adult Common Liver Flukes, Fasciola hepatica Linn., 1758Journal of Parasitology, 1957
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951