Decreased Bone Mineral Density in Patients with Pustulosis palmaris et plantaris

Publisher Website
Google Scholar
Abstract
Background: Focal skeletal changes in patients with pustulosis palmaris et plantaris (PPP) are known to occur in a minority of patients. It is unknown whether these changes are unique events or whether they merely represent more progressed cases. Objective: The study was undertaken in order to investigate possible diffuse bone changes in patients with PPP. Methods: Bone mineral density (BMD) and biochemical markers of bone turnover were studied in 18 female patients and 18 age-matched controls. Results: A significant correlation was found between lower-forearm BMD and disease duration (Conclusion: Although we cannot exclude that prolonged use of topical steroids under occlusion is a confounding factor, the study suggests that PPP patients have decreased BMD due to primary pathogenic events, and that osteoporosis may be an additional problem for these patients.

This publication has 0 references indexed in Scilit: