Investigation of a Biodegradable, Implantable Antibiotic Delivery System on Rate of Wound Infection

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Abstract
Biodel, a bioabsorbable polymer, may be adapted to serve as an antibiotic delivery system for high local concentrations of drugs. In an autocontaminated, irradiated wound model with a high intrinsic infection rate, implanted gentamicin-impregnated Biodel beads prevented wound infections in the submental area of rats. Sasmor MT, Morain WD, Balestero LM, Camp BJ. Investigation of a biodegradable, implantable antibiotic delivery system on rate of wound infection.

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