LOWER LIMB AMPUTATION SECONDARY TO LARGE VESSEL INVOLVEMENT IN SCLERODERMA
- 1 October 1988
- journal article
- case report
- Published by Oxford University Press (OUP) in Rheumatology
- Vol. 27 (5) , 403-406
- https://doi.org/10.1093/rheumatology/27.5.403
Abstract
A 34-year-old woman with scleroderma was admitted to hospital with pain and weakness of her left foot. She was subsequently shown to have developed a popliteal artery occlusion associated with progressive lower limb ischaemia. This culminated in below-knee amputation. Marked intimal hyperplasia of the large vessels in the leg was noted histologically. An increasing number of cases of large vessel involvement in scleroderma, a disease that primarily affects the microvasculature, has been reported. Scleroderma should be regarded as a rare cause of large vessel peripheral vascular disease.Keywords
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