Ultrafiltration Studies on Serum Magnesium

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Abstract
OF the four major cations in human extracellular fluid, magnesium has been investigated least. This neglect may be attributed in part to difficulties in methodology, since serum contains only 1 or 2 milliequiv. of magnesium per liter. The magnesium ion, however, is a large component of intracellular fluid and bone. Numerous animal studies have demonstrated its dietary importance in intermediary metabolism.1 2 3 4 Low concentrations of serum magnesium have been reported in patients with rickets caused by vitamin D deficiency,5 diabetic ketosis during insulin therapy,6 and dietary phosphate load7 , 8 and in a child with chronic tremor and a bony lesion thought to . . .