The role of the immune system in establishment of herpes simplex virus latency ? studies using CD4+ T-cell depleted mice
- 1 March 1993
- journal article
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 133 (1-2) , 179-187
- https://doi.org/10.1007/bf01309753
Abstract
The immunological mechanisms involved in establishment of herpes simplex virus (HSV) latency were studied in normal and CD4+ T-cell depleted C57BL/6J mice following intravaginal infection. During transition from acute to latent ganglionic infection two consecutive processes were observed: first, clearance of infectious virus from the ganglia, and second, reduction of the number of infected ganglia.Keywords
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