Triangulynes A−H and Triangulynic Acid, New Cytotoxic Polyacetylenes from the Marine Sponge Pellina triangulata

Abstract
Nine new polyacetylenes, triangulynes A−H (1−8) and triangulynic acid (9), have been isolated from the marine sponge Pellina triangulata (Oceanapiidae) through cytotoxicity-guided fractionation. Structural elucidations and stereochemistry assignments were based on chemical and spectral studies.