OCCURRENCE OF HUMAN PAPILLOMAVIRUS TYPE-16 AND TYPES-18 DNA IN CERVICAL CARCINOMAS FROM JAPAN - AGE OF PATIENTS AND HISTOLOGICAL TYPE OF CARCINOMAS
- 1 January 1985
- journal article
- research article
- Vol. 76 (8) , 667-671
Abstract
By DNA hybridization, human papillomavirus (HPV) types 16 and 18 DNA sequences have been detected in 19 and 3, respectively, out of 56 cervical carcinomas from Japan. Eighteen out of 19 HPV 16-positive specimens were from squamous cell carcinomas, whereas the 3 HPV 18-positive specimens were from a squamous cell carcinoma (1/50), an adenosquamous carcinoma (1/3) and an adenocarcinoma (1/3). The occurrence of HPV 16 DNA decreased in patients over 60 yr odl (.ltoreq. 60 yr, 15/24 (44%); 60 yr <, 4/22 (18%)) (P < 0.05).This publication has 3 references indexed in Scilit:
- A new type of papillomavirus DNA, its presence in genital cancer biopsies and in cell lines derived from cervical cancer.The EMBO Journal, 1984
- Analysis of human genital warts (condylomata acuminata) and other genital tumors for human papillomavirus type 6 DNAInternational Journal of Cancer, 1982
- Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase IJournal of Molecular Biology, 1977