Evidence for embryonic prostaglandin H synthase-catalyzed bioactivation and reactive oxygen species-mediated oxidation of cellular macromolecules in phenytoin and benzo[a]pyrene teratogenesis11Preliminary reports of this research were presented at the 33rd, 34th, and 35th Annual Meetings of the Society of Toxicology, Dallas, Texas, March 1994 (Toxicologist 14:164; 1994); Baltimore, Maryland, March 1995 (Toxicologist 15:276; 1995); and Anaheim, California, March 1996 (Fundam. Appl. Toxicol. 30(Suppl. No. 1, Part 2: The Toxicologist):244; 1996); and at the 27th Annual Symposium of the Society of Toxicology of Canada, Montreal, December 1994 (Proceedings, p. 77; 1994).