Asymmetric reduction of aromatic ketones with reagents prepared from sodium borohydride and various carboxylic acids in the presence of 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose
- 1 January 1981
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- p. 900-905
- https://doi.org/10.1039/p19810000900
Abstract
Asymmetric reduction of aromatic ketones with the reagents prepared from sodium borohydride and carboxylic acids in the presence of 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose at 0 °C gives (R)-alcohols with enantiomeric excesses as high as 83%. The optimum conditions for producing maximum selectivity and maximum yield of reaction products from sodium borohydride and isobutyric acid have been examined.Keywords
This publication has 0 references indexed in Scilit: