Effects of Suxamethonium on CO2‐Production

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Abstract
Patients (18) undergoing alloplastic surgery of the hip were divided into 3 groups, each consisting of 6 patients. All operations were performed under endotracheal intubation using halothane N2O-O2 anesthesia. After a steady state as to CO2-production had been obtained, suxamethonium 1 mg kg-1 was given i.v. to the patients in group I. A maximum rise in CO2-producton of 14.8% (range: 12.9-16.8) was observed after 5 min. In group II, patients were pretreated with pancuronium 0.01 mg kg-1; no increase in CO2-production was observed. The 3rd group received a continuous infusion of suxamethonium. In this group there was an increase in CO2-production of 17.6% (range: 6.7-22.0) 5 min after start of infusion. The CO2-production then fell to the preinfusion level over the next 10 min.