Determination of Phthalic Anhydride In Workplace Air Using Reverse Phase High Performance Liquid Chromatography

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Abstract
A reverse phase high performance liquid chromatographic procedure is described for the analysis of phthalic anhydride in workplace air. A glass fibre filter was used to collect the airborne phthalic anhydride and the analyte was then desorbed and hydrolyzed with dilute aqueous sodium hydroxide. Subsequent acidification of this solution with the mobile phase enabled the phthalic anhydride to be determined as phthalic acid using UV detection.

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