THE EFFECT OF SPECIFIC ANTIBODIES ON THE INHIBITION OF LEUCOCYTE MIGRATION CAUSED BY STAPHYLOCOCCAL PEPTIDOGLYCAN

1 September 1976

journal article
research article
Published by Wiley in Acta Pathologica Microbiologica Scandinavica Section B Microbiology

Vol. 84B (5) , 315-317
https://doi.org/10.1111/j.1699-0463.1976.tb01944.x

Abstract

Specific antibodies to the various antigenic determinants of staphylococcal peptidoglycan are tested for neutralization of the inhibiting effect of peptidoglycan on leucocyte migration. Antibodies to the C-terminal D-Ala-D-Ala group of pentapeptides and to the C-terminal of the glycine bridge showed high neutralizing effect, whereas that of antibodies to the tetrapeptide and to the glycan chain was negligible. The observed neutralization by antibodies against the outermost parts of peptide chains may be due to the inhibition of contact between peptidoglycan and cells.

Keywords

This publication has 3 references indexed in Scilit:

The Immunochemistry of Peptidoglycan
Published by Elsevier ,1971
A Simple Chromatographic Method for Preparation of Gamma Globulin.
Experimental Biology and Medicine, 1960