Ryanodyl 3-(pyridine-3-carboxylate): A Novel Ryanoid from Ryania Insecticide
- 1 July 1991
- journal article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 54 (4) , 1147-1149
- https://doi.org/10.1021/np50076a043
Abstract
Ryanodyl 3-(pyridine-3-carboxylate) was isolated as a minor component from the wet CHCl3 extract of Ryania insecticide, and its structure was assigned by chemical and spectroscopic methods. This compound is essentially inactive compared with ryanodine for insecticidal activity against Musca domestica adults and Tribolium castaneum larvae, for toxicity to mice, and for competition with [3H]ryanodine at the Ca(2+)-ryanodine receptor complex of skeletal muscle.Keywords
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