Tolerance induction of alloreactive T cells via ex vivo blockade of the CD40:CD40L costimulatory pathway results in the generation of a potent immune regulatory cell
- 15 June 2002
- journal article
- Published by American Society of Hematology in Blood
- Vol. 99 (12) , 4601-4609
- https://doi.org/10.1182/blood.v99.12.4601
Abstract
Read the full review for this F1000Prime recommended article: Tolerance induction of alloreactive T cells via ex vivo blockade of the CD40:CD40L costimulatory pathway results in the generation of a potent immune regulatory cell.Keywords
This publication has 20 references indexed in Scilit:
- Cell Contact–Dependent Immunosuppression by Cd4+Cd25+Regulatory T Cells Is Mediated by Cell Surface–Bound Transforming Growth Factor βThe Journal of Experimental Medicine, 2001
- Cd4+Cd25+ Immune Regulatory Cells Are Required for Induction of Tolerance to Alloantigen via Costimulatory BlockadeThe Journal of Experimental Medicine, 2001
- IFN-α and IL-10 Induce the Differentiation of Human Type 1 T Regulatory CellsThe Journal of Immunology, 2001
- Vbeta spectratype analysis reveals heterogeneity of CD4+ T-cell responses to minor histocompatibility antigens involved in graft-versus-host disease: Correlations with epithelial tissue infiltrateTransplantation and Cellular Therapy, 2001
- CD4(+) T cells tolerized ex vivo to host alloantigen by anti-CD40 ligand (CD40L:CD154) antibody lose their graft-versus-host disease lethality capacity but retain nominal antigen responses.Journal of Clinical Investigation, 1998
- Transplantation tolerance induced by antigen pretreatment and depleting anti‐CD4 antibody depends on CD4+ T cell regulation during the induction phase of the responseEuropean Journal of Immunology, 1995
- Inhibition of Thl responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cellsPublished by Elsevier ,1994
- "Infectious" Transplantation ToleranceScience, 1993
- A Cell Culture Model for T Lymphocyte Clonal AnergyScience, 1990
- Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo.The Journal of Experimental Medicine, 1987