Sesquiterpenic lactones from Grossheimia macrocephala. Structure of grosheiminol

Abstract
From the leaves of Grossheimia macrocephala (MUSS.-PUSCHK.) D. SOSN. et TAKHT. cynaropicrin (II), isolipidiol (III) and the so far undescribed lactone grosheiminol (IV) were isolated in addition to grosheimin (I), detected in this species earlier. For grosheiminol the structure IV was derived, including relative and absolute configuration, on the basis of chemical correlation.

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