Confirmation of F13A assignment and sequence information concerning F13A‐HLA‐GLO
- 1 November 1984
- journal article
- research article
- Published by Wiley in Clinical Genetics
- Vol. 26 (5) , 385-388
- https://doi.org/10.1111/j.1399-0004.1984.tb01077.x
Abstract
The polymorphism of the blood clotting factor 13A was examined in some of the Danish material of normal families. A total of 4 alleles were recognized, with allele frequencies as follows: F13A*1 = 0.817, F13A*2 = 0.177, F13A*4 = 0.003 and a new allele F13A* 5 = 0.003. The distribution of unrelated individuals did not deviate significantly from the Hardy-Weinberg expectation. Linkage of F13A with HLA was confirmed (.cxa.z = 5.18, .cxa..theta. = 0.17 in males and .cxa.z = 0.14, .cxa..theta. = 0.37 in females). The sequence of the 3 systems F13A, HLA and GLO [glyoxalase] was found to be F13A-HLA-GLO as judged from 2 families each with a recombinant within the HLA system in males.Keywords
This publication has 2 references indexed in Scilit:
- Gentics and linkage relationships of the C3 polymorphism: discovery of C3‐Se linkage and assignment of LES‐C3‐DM‐Se‐PEPD‐Lu synteny to chromosome 19Clinical Genetics, 1983
- Polymorphism of the A subunit of coagulation factor XIII in the pacific region. Description of new phenotypesHuman Genetics, 1981