Staphylococcus aureus: times, they are a-changin'.

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Abstract
During the past 50 years, Staphylococcus aureus has been a dynamic human pathogen that has gained the deepest respect of clinicians. Its incredible success in causing disease involves characteristics associated with host susceptibility (age, chronic disease, surgery, presence of invasive devices, or impaired immunity), the specific strain (genetics, ease of colonization, virulence, and antibiotic resistance), and epidemiology (carriage, transmission, and breaches in infection-control measures). Invasive S. aureus infections are clearly associated with increased morbidity, mortality, and costs. Our inability to control these infections highlights the need for increased awareness and better prevention and treatment strategies.