Studies on the Etiology of Lymphomas in Turkeys: Isolation of Reticuloendotheliosis Virus

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Abstract
Studies of tissues from 25 normal turkey flocks and of 15 selected turkey lymphoid tumors revealed no Marek''s disease or lymphoid [avian] leukosis viruses, although reticuloendotheliosis viruses (REV) were isolated from 3 flocks (2 with a history of neoplastic disease). The REV isolates were culturally and antigenically similar to the prototype REV strain T but were low pathogenicity. Attempts failed to transmit 6 lymphoid tumors of diverse origin by inoculation into 2 strains of recipient turkeys. These data support an etiological role for REV in some though not all forms of turkey neoplastic disease.

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