Synthesis of a Valuable Precursor for the Preparation of Novel Quinolone Glycosides
- 1 January 1990
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1990 (12) , 753-754
- https://doi.org/10.1055/s-1990-21239
Abstract
The synthesis of a valuable key intermediate, 1-(2,3,4, 6-tetra-O;-acetyl-ß-D-glycopyranosyl)-3-ethoxycarbonyl-6, 7,8-trifluoro-4-quinolone, for the preparation of novel quinolone nucleosides is described starting from the reaction of ethyl 2-ethoxymethylene-3-oxo- 3-(2,3,4,5-tetrafluorophenyl) propanoate and 2,3,4,6-tetra-O;-acetyl-ß-D-glucopyranosylamine.Keywords
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