Mutational evidence for identity of penicillin-binding protein 5 in Escherichia coli with the major D-alanine carboxypeptidase IA activity
- 1 January 1979
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 137 (1) , 644-647
- https://doi.org/10.1128/jb.137.1.644-647.1979
Abstract
The defect in D-alanine carboxypeptidase IA activity in the dacA11191 mutant of Escherichia coli was correlated with a defect in the release of penicillin G from penicillin-binding protein 5. The results suggest that penicillin-binding protein 5 catalyzes the major D-alanine carboxypeptidase IA activity of the wild type and that the mutation results in a defect in the deacylation step catalyzed by this enzyme.This publication has 10 references indexed in Scilit:
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